Good morning. Barnes Vor-Tx LR in 270 129gn rounds are devastating on deer. A friend of mine used them this year up in Alberta and put it through a large bodied buck quartering to him. Also the Swift A-Frame 270 150gn round would be great on anything around so you couldn’t go wrong. I shot a large buck in Alberta two years ago. He was facing me. I hit him in the side of his neck and it traveled the entire length of his body. We recovered it in his back hip joint. DEVASTATING!!!!! Didn’t move a muscle. That was with a Barnes LRX. I shoot both a .30-378 and .257 Weatherby. Both shoot the LRX and Swift A-Frames extremely accurately which is what truly counts. Hope his helps you out